Roxane Simeone Selected Research

Tuberculosis (Tuberculoses)

1/2017	ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis.
1/2017	Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection.
1/2016	Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access.
6/2015	ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection.
1/2013	Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis.
9/2012	ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells.
3/2012	Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation.
4/2009	Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Roxane Simeone Research Topics

Disease

8	Tuberculosis (Tuberculoses) 01/2017 - 04/2009
5	Infections 01/2022 - 04/2012
3	Rupture 01/2017 - 02/2015
1	Bites and Stings (Sting) 01/2017
1	Bacterial Infections (Bacterial Infection) 07/2011

Drug/Important Bio-Agent (IBA)

3	Type VII Secretion SystemsIBA 01/2017 - 06/2015
3	VaccinesIBA 01/2017 - 04/2012
2	CytokinesIBA 01/2022 - 07/2011
2	LipidsIBA 01/2017 - 01/2013
2	Virulence Factors (Pathogenicity Factors)IBA 01/2017 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 03/2012
2	AntigensIBA 01/2017 - 04/2009
1	MucinsIBA 01/2022
1	Antimicrobial PeptidesIBA 01/2022
1	InflammasomesIBA 01/2017
1	Interferon Type IIBA 01/2017
1	AerosolsIBA 01/2017
1	NucleotidesIBA 01/2017
1	CationsIBA 02/2015

Therapy/Procedure

1	Therapeutics 06/2015